01In brief
MassChallenge is a Boston-headquartered global network of nonprofit startup accelerators that supports early-stage companies without taking equity. Published accounts date its beginnings variously to 2008, 2009, and 2010. A 2014 Globes profile gave 2010, while the organization's current About page says it has supported startups since 2009. The network has operated programs in the United States, Israel, Switzerland, Mexico, Africa, and Asia. MassChallenge's current figures report more than 5,000 startups supported, over $16 billion raised, and 90,000 jobs created. Its Jerusalem-based Israel program, launched in 2016, connects Israeli and international entrepreneurs with mentors, corporate partners, and investors while offering equity-free awards to selected startups.
02Overview and Model
MassChallenge operates as a nonprofit accelerator open to early-stage startups from any sector, without requiring equity, shares, or other compensation.[1][2] Its programs are intended to help entrepreneurs build business traction, while its About page says it focuses on founders addressing complex, regulated, and high-stakes problems across five Challenge Areas.[1][5]
The core accelerator model has provided a four-month program comprising mentorship, workspace, networking, professional advice, and access to potential investors.[3] Outstanding companies compete for equity-free cash prizes; historical prize pools reached roughly $1.5–$2 million, supplemented by professional services valued at about $10 million.[3][2] The only financial requirement described by founder John Harthorne was a $99 application fee, which the organization frequently waived and said was intended to deter duplicate submissions rather than generate revenue.[8]
Acceptance is competitive. In an illustrative year, MassChallenge's Boston program received around 1,600 applications and admitted 128 companies.[3] At the Israel program's 2016 opening, 48 startups were selected from approximately 500 projects, including about 150 submissions from outside Israel.[9] At the 2022 Israel finale, judges considered each company's growth during the program, clarity of its path to success, and potential positive impact in its sector.[10]
03Origins and Early Growth
MassChallenge was founded in Boston. John Harthorne served as founder and chief executive officer during its early expansion, while a 2014 Globes profile identified Akhil Nigam as a co-founder.[3][4] By May 2016, during its first six years of operation, 835 companies had participated in its global programs, raising more than $1 billion, generating annual revenue exceeding $500 million, and creating 8,500 jobs.[9]
The Jewish Virtual Library described MassChallenge as the largest startup contest in the world, noting that its 2014 program awarded more than $1.75 million in grants and over $10 million in additional prizes.[11] That year, Israeli agricultural technology firm AutoAgronom placed among the final 25 participants and was the competition's only agricultural technology company.[11] AutoAgronom's smart drip-irrigation system used soil sensors and computer algorithms to optimize water, fertilizer, and pest-control delivery. By November 2014, it had been deployed across 13 countries and 70 crop types; UK farmers using it reportedly reduced water use by 30%, increased crop yields by 28%, and decreased pesticide use by 70%.[12]
By October 2015, MassChallenge operated centers in Boston and London and had announced Jerusalem as its third global center.[2] Its program was open to startups from any sector while seeking young companies with high-impact ambitions; the organization did not prescribe a particular measure of success, treating an initial public offering, a sale, or sustained company growth as possible positive outcomes.[3]
04Expansion to Jerusalem
MassChallenge's decision to open an Israel program reflected the organization's view of Israel as a natural partner. Harthorne described the country as an innovation center with a strong entrepreneurial ecosystem and argued that connecting Israeli and Boston communities could generate opportunities for globally ambitious companies. He also noted that Israeli and Jewish entrepreneurs had created value for Massachusetts.[3]
Plans for the Jerusalem center were announced in October 2015 as part of the Jnext initiative, with the Ministry of Jerusalem and Heritage, the Jerusalem Development Authority, and the Jerusalem Municipality supporting the project.[2] The five-year establishment and operating budget was estimated at approximately $15 million, with funding involving those public bodies, MassChallenge, and U.S.-based donors.[6] Additional private-sector supporters included Combined Jewish Philanthropies, The Kraft Group, Bank Hapoalim, EMC, and the law firm Herzog Fox Ne'eman.[13]
The Jerusalem center was formally launched in January 2016 after MassChallenge considered dozens of candidate cities.[6] It later operated in Jerusalem's Mahaneh Yehuda market.[9] The launch event drew roughly 800 attendees, including startup founders, investors, and senior Israeli technology figures.[6] A showcase of 17 Israeli startups was featured, bringing together business leaders, investors, and entrepreneurs.[14]
Israel Ganot—founder of Gazelle and a veteran executive at eBay and PayPal—was named managing director of MassChallenge Israel.[13] The program's stated goal was to support 100 startups within its first two years, serving Israeli companies and international entrepreneurs seeking access to Israel's startup environment.[14] The launch built on earlier engagement: during the preceding year, seven Israeli startups had been accepted into the Boston program and five into the London program.[14]
05The Israel Program in Practice
The Israel accelerator is sector-agnostic and typically works with roughly 30–50 companies annually.[15][7] At its 2016 opening, approximately 500 projects were considered, including around 150 from outside Israel, and 48 startups were selected.[9] By 2019, MassChallenge selected 52 startups from applicants representing 41 countries, with nearly 100 applications from India; finalists came from Israel, India, Colombia, South Africa, and the United Kingdom.[16]
Participants receive more than 100 hours of sessions, workshops, and events over the four-month program, together with introductions to mentors, corporate partners, and investors, shared office space, and peer mentorship.[7] In 2021, managing director Yonit Serkin described a community-based approach in which volunteer mentors and sector experts met with startups weekly to establish goals and consider routes to market.[17] She said about one-third of the companies MassChallenge Israel worked with came from outside Israel and that ten startups were brought to the United States each year to build networks and work toward their next milestones.[17]
Judging panels have included experts from organizations such as Accenture, Google, BCG, Kimberly-Clark, Elta Israel Aerospace Industries, Rafael Advanced Defense Systems, and Gett.[16] Selection criteria have emphasized company growth during the program, a clear path to success, and potential positive impact in the relevant sector.[10] Top performers can receive equity-free cash awards.[7] Winners in the 2022 and 2023 cohorts also earned investor roadshows to Boston and New York to meet prospective investors, customers, partners, business leaders, and officials.[10][18]
Specialized tracks have been added over time. The 2022 cohort included an Impact Series led by Arc Impact and a Better Plate track focused on alternative-protein solutions in collaboration with the Modern Agriculture Foundation.[19] The 2023 cycle featured a Climate and Environment track sponsored by Arc Impact and another Better Plate track run with the Modern Agriculture Foundation.[18] These tracks channel expertise from relevant partners to startups addressing particular industries or challenge areas.
06Cohort Highlights and Alumni
Across successive cohorts, MassChallenge Israel has produced a diverse range of winning companies. The 2021 program's nine winners included ventures working on phage-based crop protection, waterless sanitation, at-home fertility monitoring, personalized 3D printing of tissues and organs, and audible wayfinding for people with visual impairments.[20] By the end of that program cycle, the Israel operation's 249 alumni companies had raised more than $530 million and created 12,000 direct and indirect jobs globally.[20]
The 2022 cohort spanned startups from 12 countries and 30 cities and produced ten winners: AlgaHealth, Atiko Technologies, Cuspa, IntraGel Therapeutics, Liquid360, MadeRight, Non-Polymeric3D, PoLoPo, RideRadar Technology, and Supplyve.[10] Their work covered biotechnology and life sciences, software and SaaS, cybersecurity, e-commerce, and mobility. Biotechnology and life sciences represented 32% of cohort companies, while software and SaaS represented 29%.[10] By then, MassChallenge Israel had more than 300 alumni companies, which had collectively raised about $750 million and created 11,000 direct and indirect jobs.[10]
The 2023 program named nine winners: Amis AI of Colombia; CODA, H2Oll, McFly, Origametria, Pregnantech, RealizeMD, and TextRe of Israel; and Servr of the United Kingdom. DairyX was recognized as the top performer in the Better Plate track.[18] By that cohort, more than 375 companies had graduated from the Israel Early-Stage Accelerator, and MassChallenge Israel alumni had collectively raised more than $1.1 billion.[18]
The program's cumulative figures, as displayed on MassChallenge's Israel page, report more than 400 startups accelerated, over $1.7 billion in funding raised, a 73% active-alumni rate, 43% female founders, and 12 exits.[7] The page also reports that 57% of the Israeli companies supported by the program are located outside Jerusalem, reflecting the accelerator's national reach.[7]
A 2019 analysis of the first three program rounds highlighted Jerusalem-based participants specifically. Forty Jerusalem companies had raised $50 million of the Israel program's total $150 million in alumni fundraising, employed 372 people, and generated $6 million of the participating companies' combined $22 million in revenue.[21] Across those early cohorts, 41% of participating companies had at least one woman founder, and those companies had raised more than $47 million.[21]
07Significance and Global Scale
Beyond the Israel program, MassChallenge developed a broad international footprint. A 2023 report described it as a U.S.-headquartered global network with eight locations and accelerator programs in Israel, Switzerland, Mexico, the United States, Africa, and Asia.[1] Since its launch, the organization had awarded more than $17 million in equity-free cash and prizes.[1]
MassChallenge's alumni portfolio grew substantially over time. By July 2022, CTech reported that the global network had more than 2,450 alumni, which had collectively raised $6.2 billion, generated $3 billion in revenue, and created 157,000 jobs.[10] The organization's current figures report more than 5,000 startups supported since inception, over $16 billion raised, and 90,000 jobs created through collaborations with more than 500 partners worldwide.[5]
MassChallenge's reach drew formal recognition from the U.S. federal government. A 2016 White House fact sheet highlighted the Boston program as a no-equity accelerator for early-stage startups, noting that since 2010 it had accelerated 873 startups that raised $1.7 billion and helped create more than 50,000 jobs.[22] That year, MassChallenge Boston launched or expanded two inclusion-focused initiatives: Women in MassChallenge, serving female founders, and Bridge to MassChallenge, a series of startup bootcamps intended to support entrepreneurs in underserved communities.[22]
The organization also operated in health technology. MassChallenge HealthTech managed PandemicX, a six-month pilot jointly sponsored by the HHS Office of the Assistant Secretary for Health and the Office of the National Coordinator for Health IT. From December 2021 through June 2022, its inaugural cohort connected 15 startup teams with government leaders on priorities including health equity and access to care. Participants designed and deployed digital public-health solutions emphasizing an equitable COVID-19 response and recovery.[23]
08Controversies and Discrepancies in Reported Data
Published sources give conflicting dates for MassChallenge's origins. A 2014 Globes profile said it was founded in 2010, while a 2015 Globes report said it was founded in 2008.[4][3] JNS described the organization as launching in 2009.[1] MassChallenge's official pages also differ: its current About page says it has supported startups since 2009, while a separate announcement said it was founded and initially launched in Boston in 2010.[5][24] The sources do not reconcile these dates.
Historical portfolio figures also vary by date and terminology. Globes reported in 2016 that 835 companies had participated and created 8,500 jobs, while CTech reported in 2022 that more than 2,450 alumni had created 157,000 jobs.[9][10] A 2023 JNS report instead referred to more than 3,000 participating startups.[1] These are dated snapshots using terms such as companies, alumni, and participants, rather than a single reconciled statistical series.
Sources
- 1Jewish News Syndicate, Forty-nine Israeli startups learn business basics in MassChallenge program, accessed on October 15, 2026.
- 2Calcalist, Startup accelerator MassChallenge begins operating in Israel, accessed on October 15, 2026.
- 3Globes, MassChallenge mulls Israel accelerator branch, accessed on October 15, 2026.
- 4Globes, Israel and the Boston tech comeback, accessed on October 15, 2026.
- 5MassChallenge, About Us, accessed on October 15, 2026.
- 6Ynet, The world's largest startup accelerator was launched in Jerusalem, accessed on October 15, 2026.
- 7MassChallenge, Israel Program, accessed on October 15, 2026.
- 8The Times of Israel, Jerusalem Accelerator Announcement, accessed on October 15, 2026.
- 9Globes, Startup accelerator opens in Jerusalem, accessed on October 15, 2026.
- 10CTech by Calcalist, MassChallenge Israel announces 10 startups as its 2022 accelerator program winners, accessed on October 15, 2026.
- 11Jewish Virtual Library, State-to-State Cooperation: Massachusetts and Israel, accessed on October 15, 2026.
- 12Jewish Virtual Library, Israel Science & Technology: Agro-Technology, accessed on October 15, 2026.
- 13The Times of Israel, World's Biggest Accelerator Makes Aliyah, accessed on October 15, 2026.
- 14MassChallenge, Israel 2016 Launch, accessed on October 15, 2026.
- 15CTech by Calcalist, Choosing an accelerator? This is what startups should look for, accessed on October 15, 2026.
- 16The Times of Israel, 52 Global Startups for 2019 Program, accessed on October 15, 2026.
- 17CTech by Calcalist, “I absolutely think that founders need to be irrationally passionate and driven about their companies", accessed on October 15, 2026.
- 18CTech by Calcalist, MassChallenge Israel unveils winners of the 2023 early-stage accelerator, accessed on October 15, 2026.
- 19MassChallenge, Israel 2022 Program Winners, accessed on October 15, 2026.
- 20The Jerusalem Post, MassChallenge winners include fertility treatment, 3D organ printer, accessed on October 15, 2026.
- 21Globes, Israeli Mass Challenge entrepreneurs raise $150m, accessed on October 15, 2026.
- 22U.S. National Archives, FACT SHEET: Celebrating President Obama’s Top 10 Actions to Advance Entrepreneurship, and Announcing New Steps to Build on These Successes, accessed on October 15, 2026.
- 23U.S. National Archives, The White House Archives (Biden), accessed on October 15, 2026.
- 24MassChallenge, Strategic Growth Initiatives, accessed on October 15, 2026.
IsraelPedia Question & Answers
What is MassChallenge?
MassChallenge is a Boston-headquartered global network of nonprofit startup accelerators that supports early-stage companies without taking equity. Its programs have operated in the United States, Israel, Switzerland, Mexico, Africa, and Asia. The organization's current figures report more than 5,000 startups supported, over $16 billion raised, and 90,000 jobs created through collaborations with more than 500 partners worldwide.
How does the MassChallenge accelerator program work?
MassChallenge's core accelerator model provides a four-month program that includes mentorship, workspace, networking, professional advice, and access to potential investors. It is open to early-stage startups from any sector and requires no equity, shares, or other compensation. Outstanding companies compete for equity-free cash prizes, with historical prize pools reaching roughly $1.5–$2 million, supplemented by professional services valued at about $10 million. The only financial requirement described by founder John Harthorne was a $99 application fee, which the organization frequently waived.
When and why did MassChallenge open a program in Jerusalem?
MassChallenge formally launched its Jerusalem center in January 2016, after considering dozens of candidate cities. The decision reflected the organization's view of Israel as an innovation center with a strong entrepreneurial ecosystem, with founder John Harthorne arguing that connecting Israeli and Boston communities could generate opportunities for globally ambitious companies. Plans for the center had been announced in October 2015 as part of the Jnext initiative, with support from the Ministry of Jerusalem and Heritage, the Jerusalem Development Authority, and the Jerusalem Municipality, among other public and private backers.
Who has supported and funded MassChallenge Israel?
MassChallenge Israel was established with backing from the Ministry of Jerusalem and Heritage, the Jerusalem Development Authority, and the Jerusalem Municipality, as well as MassChallenge itself and U.S.-based donors. The five-year establishment and operating budget was estimated at approximately $15 million. Additional private-sector supporters included Combined Jewish Philanthropies, The Kraft Group, Bank Hapoalim, EMC, and the law firm Herzog Fox Ne'eman.
What results has MassChallenge Israel produced across its alumni?
As displayed on MassChallenge's Israel page, the program reports more than 400 startups accelerated, over $1.7 billion in funding raised, a 73% active-alumni rate, 43% female founders, and 12 exits. By the end of the 2023 cohort, more than 375 companies had graduated from the Israel Early-Stage Accelerator, with alumni collectively raising more than $1.1 billion. The program also reports that 57% of the Israeli companies it has supported are located outside Jerusalem, reflecting its national reach.
What specialized tracks has MassChallenge Israel introduced?
MassChallenge Israel has added specialized tracks to focus expertise on particular industries. The 2022 cohort included an Impact Series led by Arc Impact and a Better Plate track focused on alternative-protein solutions in collaboration with the Modern Agriculture Foundation. The 2023 cycle featured a Climate and Environment track sponsored by Arc Impact and another Better Plate track run with the Modern Agriculture Foundation.
Are the founding date and alumni statistics for MassChallenge consistent across sources?
Published sources give conflicting dates for MassChallenge's origins: a 2014 Globes profile cited 2010, a 2015 Globes report said 2008, and JNS described the organization as launching in 2009. MassChallenge's own pages also differ, with its current About page stating it has supported startups since 2009 while a separate announcement said it was founded and initially launched in Boston in 2010. Historical portfolio figures similarly vary, as different reports use differing terms such as companies, alumni, and participants and reflect different points in time, rather than forming a single reconciled statistical series.